Treatments at Bnoon
Ovulation Induction is usually one of the first treatment options utilized if a woman is struggling to conceive.
It is the process of stimulating ovulation by using medications. Women who do not ovulate regularly are good candidates for this type of treatment.
Induction of ovulation with gonadotropins requires a patient and physician commitment.
The injectable drugs are hormones that your pituitary gland normally produces. Although FSH is the hormone primarily responsible for follicular development, both FSH and LH play a role in the normal development and ovulation of ovarian follicles. LH is normally responsible for triggering ovulation when a mature follicle is present.
Each of these drugs acts directly on the ovaries and do not have activities elsewhere in the body. Example:
The injectable drugs are hormones that your pituitary gland normally produces. Although FSH is the hormone primarily responsible for follicular development, both FSH and LH play a role in the normal development and ovulation of ovarian follicles. LH is normally responsible for triggering ovulation when a mature follicle is present.
Each of these drugs acts directly on the ovaries and do not have activities elsewhere in the body. Example:
Gonal F Pen is given subcutaneously. Gonal F comes in multi-dose Pen (300 – 450 – 900 – 1200 IU).
Menopur is given subcutaneously. Menopur comes in ampule (75 – 600 – 1200 IU).
Merional is given intramuscular or subcutaneously. Merional comes in ampule (75 – 150 IU).
Menogon is given intramuscular or subcutaneously. Merional comes in ampule (75 IU).
HCG (Human Chorionic Gonadotropin): Its action is to trigger the final maturation of the egg and ovulation. Examples:
Pregnyl–Choriomon–Choragon (5000 – 10000 IU) is given intramuscularly.
Ovidrel-Ovitrelle (250 µg) is given subcutaneously.
Indications for Treatment In women who do not ovulate on their own (anovulation) like cases of Polycystic Ovaries. It is also used in women who do ovulate on their own like cases of unexplained infertility and endometriosis. These drugs are used to produce more follicles in the ovaries in a controlled fashion and are used alone or in combination with tablets like Clomid and others. For most women, any of the above mentioned drugs may be appropriate to use. However, in certain situations, one drug may be more advantageous to you. The choice of medications will be discussed during your counselling session prior to initiating therapy.
Monitoring
Menopur is given subcutaneously. Menopur comes in ampule (75 – 600 – 1200 IU).
Merional is given intramuscular or subcutaneously. Merional comes in ampule (75 – 150 IU).
Menogon is given intramuscular or subcutaneously. Merional comes in ampule (75 IU).
HCG (Human Chorionic Gonadotropin): Its action is to trigger the final maturation of the egg and ovulation. Examples:
Pregnyl–Choriomon–Choragon (5000 – 10000 IU) is given intramuscularly.
Ovidrel-Ovitrelle (250 µg) is given subcutaneously.
Indications for Treatment In women who do not ovulate on their own (anovulation) like cases of Polycystic Ovaries. It is also used in women who do ovulate on their own like cases of unexplained infertility and endometriosis. These drugs are used to produce more follicles in the ovaries in a controlled fashion and are used alone or in combination with tablets like Clomid and others. For most women, any of the above mentioned drugs may be appropriate to use. However, in certain situations, one drug may be more advantageous to you. The choice of medications will be discussed during your counselling session prior to initiating therapy.
Monitoring
It is essential that close monitoring with ultrasound and sometimes blood tests be done to reduce the chances of adverse consequences and to increase the chances of success.- Please call the center when your period starts (day 1 of your cycle with normal flow) to arrange for ultrasound and clinic visit to see the physician.
- Medicines are usually started on day 2-3 of the cycle. Baseline ultrasound is required before starting the medicine.
- The ultrasound determines how many follicles are developing and how mature they are, based on their size.
- After the baseline tests, you will take the medicine 5-9 days then return for an ultrasound and the physician will inform for any adjustments in medicine dosage and return visits, if required, until the follicles are mature.
- Once we have reached our goals for follicle development HCG will be given to induce the final maturation of the egg and ovulation. Do not take the HCG until you are told to.
- We generally recommend timing of intercourse in the next 2 days after HCG injection.
- The earliest pregnancy test can be done is 14 days after the HCG was given. Please call the treatment coordinator to communicate your result of pregnancy test.
Adverse Reactions and Risks to Ovarian Stimulation
- Local irritation at injection site
- Dizziness, nausea, headaches, mood swings irritability, hot flashes, breast fullness or tenderness
- Ovarian cyst formation/enlargement and twisting
- Ovarian Hyperstimulation Syndrome
- Multiple pregnancy
- Cycle cancellation
3 Frequency of Therapy: 3-6 cycles
Informed Consent for the treatment is essential and has to be completed by both husband and wife.
Informed Consent for the treatment is essential and has to be completed by both husband and wife.